Mechanism of action of sedating antihistamines

While having been shown to have some efficacy in preventing motion sickness, these are a controlled substance with a high abuse potential, and therefore should be prescribed with caution.This fact, along with its sedation properties, make it a poor choice.

Scopolamine, which is most commonly prescribed as a transdermal patch, should be administered at least 30 minutes prior to exposure to motion stimuli.

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[ Read the disclaimer | Adults: Allergic rhinitis, seasonal/perennial: 5 mg po qd. In patients with liver or renal impairment, a starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.

Some experts report the dose can be safely doubled by wearing either two patches or by supplementing the patch with oral scopolamine.

Mixture of 1:1 salt consisting of 8-chlorotheophylline and diphenhydramine.

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Scopolamine’s effectiveness is likely due to its central anticholinergic properties.

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  1. BOC were playing New Orleans on the 24th, so they weren't exactly going to be "in the area" for this gig on the 25th... Boris Badenov Jul 22, 2016 PM They filled in for Blue Oyster Cult, nobody had ever heard of LS. How can you have a HIT if we've never heard the song???